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Thermodynamics in Neurodegenerative Diseases: Interplay Between Canonical WNT/Beta-Catenin Pathway-PPAR Gamma, Energy Metabolism and Circadian Rhythms

Of the 3 ARs subtypes (1AR, 2AR, and 3AR) expressed in the heart, 1ARs are the most abundant (~7580%) with some expression of 2ARs (~1520%) and minimal expression of 3AR

This refined understanding of CNS scarring underscores the dynamic roles of both astrocytes and fibroblasts, shifting the paradigm from a simplistic view of the glial scar to a more nuanced appreciation of the interplay between glial and fibrotic components

Cancer Discovery (2017) 7(11):123847

The GPx can lower ROS levels by acting as a catalyst in the reduction of hydrogen peroxide, which transforms to water or alcohol (Andrs et al., 2022) Lowering GSH activity is another way