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Nat Rev Endocrinol , 5 , 374-381

Scally, C

Importantly, atrophic signaling can be maintained in myotubes derived from MuSCs isolated from atrophied muscle 19,35 , and our studies showed in vivo hyperglycemia impaired myotube size after in vitro culture, likely resulting in the observed reductions force producing capacity of 3D cultures

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