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The elabela-APJ axis could mitigate neuronal ferroptosis following ischemic stroke, and the ELA-32 peptide may be a potential therapeutic candidate for ischemic stroke and cardiovascular diseases

Chavez M, van Dijk G, Arkies BJ, Woods SC

Reactive nitrogen species (RNS) are neutralized by the same systems that are responsible for the neutralization of reactive oxygen species, ROS

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The extracellular L-cysteine/L-cystine redox balance, and thus the synthesis of GSH, is finely regulated by the intracellular conversion of L-cystine into L-cysteine (10), and its impairment is related to oxidative stress and other pathological disorders

(3) documentation of no personal or family history of medullary thyroid carcinoma or MEN2