acetaminophen toxic metabolite glutathione Pathway (toxic doses), Pharmacokinetics Reducing the effects of drug
Description
21 Shenoy, S., Chaskar, U., Sandhu, J

Machado V, Cabral A, Monteiro P, et al

[12] What laboratory tests should be monitored

Multiple liver transplants required at supratherapeutic doses with fetal death

(1) Glutathione c nhiu li ch khc nhau i vi da v c th con ngi, c th k n nh: Glutathione tn ti di hai dng: Reduced glutathione (GSH, hay L-glutathione) v oxidized glutathione (GSSG)
Oral dihexa shows wider half-life variability (1.84.2 hours) due to genetic polymorphisms in CYP3A4 and other hepatic enzymes some subjects are rapid metabolizers, others slow
