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Approach: His work emphasizes evidence-based microbiome science, long-term safety, and a systems-based understanding of how microbes influence human health

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Recent work has increasingly emphasized the role of these integrative systemsincluding energy availability, microbiota-derived metabolites, and neuroendocrine stress responsesin modulating or even overriding hormonal effects [15,16,17,18,19], highlighting the need for a systems-level perspective