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Notably, melatonin plays a dual role: it acts as an immunostimulant in basal or immunosuppressed states, enhancing defenses against infections and tumors, while serving as an anti-inflammatory agent during excessive immune activation, such as in septic shock [18,19,20] (Figure 3)

Study on Radix Scrophulariae for the treatment of hyperthyroidism rat model of yin deficiency based on urine metabonomics

Since isolation of NSCs can sometimes prove to be infeasible due to the potential complications of the procedure and their low availability, other researchers are looking into reprogramming peripheral blood mononuclear cells (PBMCs) isolated from donors peripheral venous blood into induced iNSCs [112]

Z.LoomisD.GrosseY.El GhissassiF.Benbrahim-TallaaL.GuhaN.et al

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Lancet Neurol 2022;21:922-36.ArticlePubMedPMC 13