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A second report utilized a mouse model in which retinal degeneration was induced following the administration of sodium iodate (SI) (86)

Evaluation of the Mechanism of the Brain Delivery As the main principle of the transporter-mediated approach is the use of the transporters for brain delivery of drugs, the confirmation of the utilization of the specific transporter by (pro)drugs, or nanocarriers for the BBB uptake should be confirmed

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Supporting co-IP data, we observed a pronounced and dose-proportional increase of bioluminescence after cellular SP3N treatment, indicative of drug-induced ternary complex formation (Fig

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