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Yes, this is a special form of skin pigmentation called m elasma
A central obstacle lies in their complex etiology: most cases result from polygenic contributions of multiple variants classified as benign, in interaction with multifactorial exposures across the lifespan
Eosinophil-derived MMP-9 is found in basal cell and squamous cell carcinomas95,96 and in bullous pemphigoid lesions.97 MMP-9 cleaves type XVII collagen (BP 180), a transmembrane molecule of the epidermal hemidesmosome, likely contributing to or causing basement membrane zone separation in bullous pemphigoid

We then convened a test panel that included me, writer Arriana Vasquez, and photo editor Connie Park

[DOI] [PMC free article] [PubMed] [Google Scholar] 142.Kang JH, et al
