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Remodeling of the left ventricle (LV) refers to the adaptation of the heart pathologically to mechanical, neurohormonal, as well as genetic changes, the regulation of its dimension, surface structure, and function

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A recent proteomic study suggested altered mitochondrial function in the cerebrovasculature isolated from deceased cognitively healthy E4 carriers compared to non-E4 carriers, indicating that cerebrovascular bioenergetics may indeed be altered in cognitively healthy E4 carriers (Ojo et al., 2021)

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Cancer 125(11):1855-1866, 2019

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