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Scratch-wound assays mainly evaluate two-dimensional closure across a culture surface and are sensitive to wound width, cell confluence, proliferation rate, matrix coating, and serum concentration

Table 1 presents a listing of compounds in Family 1 , drawn to mimetics, and Famillies 2-5 drawn to antagonists, all of which have been synthesized and analyzed according to the procedures described above

10.1111/j.1753-4887.2008.00031.x [DOI] [PubMed] [Google Scholar] 9

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Community sources describe bedtime dosing to minimize impact Facial flushing within 30-60 minutes, lasts 1-2 hours Appetite suppression community sources describe reductions exceeding 50% during the loading phase Libido increase pronounced