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Although no FASN inhibitor has yet received regulatory approval, the FASN inhibitor TVB-2640, alone or combined with omeprazole, has progressed to Phase II clinical trials [382, 384]

Further work utilizing whole-cell fluorescence-based library assays also revealed a reduced specificity at the P6 position where glutamic acid was originally suggested to be strongly favored [4]

Overexpression of GSTA1 significantly alleviated steatosis induced by oleic acid (OA) in hepatocytes or a high-fat diet (HFD) in the mouse liver

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minimize moisture exposure [5]