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US National Library of Medicine.ClinicalTrials.gov[online], (2013)
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BACH1 effectively regulates multiple cellular processes like cell growth, differentiation, senescence, and apoptosis

Moreover, excessive Fe 2+ overload would further feed back into apoptosis by inducing ER stress and activating pro-apoptotic pathway (28), which ultimately worsen metabolic dysfunction and liver injury

It has been widely used in anti-aging and cosmetic products for decades without any adverse effects, and can be easily incorporated into creams, liposomes, foams, or subcutaneous injections

Forman HJ, Maiorino M, Ursini F (2010) Signaling functions of reactive oxygen species
