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Here, we elucidate the molecular mechanism underlying this interaction, discovering two short linear motifs in NCOA4 that each bind GATE16 with weak affinity
Naveen Kumar, University of Michigan, United States Veronica Demicheli, Universidad de la Repblica, Uruguay Updates Copyright 2025 Khan, Bhagwath, Ajmal, Ansari, Lohani, Raghunandana and Luqman
Chen Z, Inague A, Kaushal K, Fazeli G, Schilling D, Xavier da Silva TN, et al
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Studies have confirmed that it can inhibit the expression of IL-1, IL-6, TNF- and cyclooxygenase 2 (COX-2, which plays an important role in apoptosis and tumorigenesis), and increase the expression of HSP-70 and heat shock factor 1 (HSF-1) values in the rat cochlea [212]
The anticancer flavonoid baicalein induces cell death related to autophagy by activating AMPK/ULK1 and reducing components of the mTORC1 complex [178]
