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doi: 10.1021/tx970136j

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It was observed that the upregulation of the Bcl-2 gene, which inhibits most types of apoptotic cells, and the downregulation of the Bax gene, which can promote apoptosis, were detected in cells treated with EGCG [88]
Shauly-Aharonov M, Shafrir A, Paltiel O, Calderon-Margalit R, Safadi R, Bicher R, Barenholz-Goultschin O, Stokar J (2021) Both high and low pre-infection glucose levels associated with increased risk for severe COVID-19: new insights from a population-based study

The resulting damage intensifies cellular dysfunction and suppresses mitochondrial respiration, thereby aggravating the bioenergetic failure that underlies severe sepsis (Vctor et al., 2009
