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The PRISMA statement for reporting systematic and metaanalyses of studies that evaluate interventions: explanation and elaboration

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The research found no negative effects on carbohydrate metabolism across all dose ranges studied

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However, do not discontinue prescribed B12 treatment without medical advice, particularly if you have pernicious anaemia or confirmed deficiency, as untreated B12 deficiency can lead to irreversible neurological damage

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If you experience any combination of these symptoms, particularly if you have risk factors, it is important to seek medical assessment promptly

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Tirzepatide enhances fat oxidation, allowing a more efficient burning of stored fat, leading to improved body mass composition and reduced fat mass

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