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Pain Pract., 20 , 838849
The PRISMA statement for reporting systematic and metaanalyses of studies that evaluate interventions: explanation and elaboration

The research found no negative effects on carbohydrate metabolism across all dose ranges studied
However, do not discontinue prescribed B12 treatment without medical advice, particularly if you have pernicious anaemia or confirmed deficiency, as untreated B12 deficiency can lead to irreversible neurological damage

If you experience any combination of these symptoms, particularly if you have risk factors, it is important to seek medical assessment promptly

Tirzepatide enhances fat oxidation, allowing a more efficient burning of stored fat, leading to improved body mass composition and reduced fat mass
