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Ethics declarations Competing interests John Varga- Receives consulting fees from, and owns equity shares in TeneoFour

J Biomed Mater Res A

Current obstacles to successful local or systemic delivery of peptides include poor absorption, enzymatic degradation, and mucociliary clearance

Disclosure of interest: Christoph Kurmann: Grant from the Department of Teaching and Research, Insel Group AG (outside the submitted work)

Oral B12 relies on stomach acid, digestive enzymes, and a healthy gut lining

Urinary excretion of lesinurad was ~36%66% lower with moderate renal impairment and ~81% lower in severe renal impairment compared with subjects with normal renal function