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In experiments with T51B and RL-34 epithelial cells, we have found evidence that curcumin-iron complexation abolishes both curcumin-induced autophagy and apoptosis, together with the tumorigenic action of iron overload.

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Overexpression of Cited2 enhanced TGF--mediated transcription of a Smad-Binding Element-containing luciferase reporter construct, SBE4-Luc

it also correlated with altered activities of redox-sensitive enzymes in mitochondria isolated from mouse brain (e.g., aconitase-2

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