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Moreover, the largest clinical trials included in the meta-analysisand, in consequence, those with more power in the analysisused vitamins E and C, i.e., supplements without proven beneficial effects

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Figure 1 Microglia-resultant reactive chemical elemental species react ROS and activate the well-characterized apoptotic indicator regulation as kinase-1 (ASK1)/ p38 -dependent, Kv2.1-mediated K + current surge ( 2+ has shown to be essential for p75 neurotrophin receptor (NTR)-mediated cell death and seems to reduce K + /Cl co-transporter 2 (KCC2) in case of oxygen-glucose deficiency in cells