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Hesperetin protects against palmitate-induced cellular toxicity via induction of GRP78 in hepatocytes

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Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron

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Other chemical agents, such as those used in laboratories and industries, natural chemicals (e.g., alpha-amanitin), and herbal remedies (two prominent examples being kava, though the causal mechanism is unknown, and comfrey, through pyrrolizidine alkaloid content) can also induce hepatotoxicity

Normal CBF at birth is lower than the adult rate of 50ml/min/100g (Chiron et al., 1992)