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Collectively, these studies provide evidence that the L-carnitine system is differentially impacted by APOE genotypes with age and following L-carnitine challenge which could later contribute to AD pathogenesis through bioenergetics deficits, FA toxicity, and cerebrovascular dysfunction in E4s, especially in females

The viability of C2C12 myocytes was evaluated using Cell Counting Kit-8 (Dojindo Laboratories)

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doi:10.1126/sageke.2005.18.pe12

Atrial fibrillation is associated with the fibrotic remodelling of adipose tissue in the subepicardium of human and sheep atria

They also tend to grow and proliferate rapidly, and large-scale screening can easily be performed