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Targeting pyruvate dehydrogenase kinase signaling in the development of effective cancer therapy

Loens et al

Animal data covers relatively short treatment cycles, and extrapolating beyond that requires clinical judgment

In this context, melittin has been shown to impede in vitro and in vivo HCC cell movement via lowering Rac1-dependent processes (Haque et al., 2023)

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22 - 25 Likewise, unlike the secretion of adrenocorticotropic hormone, adrenalin and corticosteroids which are released into the bloodstream to meet the threat, these integrative beneficial effects could not be achieved with the administration of corticosteroids