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In both cases, this suggests that interactions of these neurons with ASJ could modulate polyQ aggregation (Fig 2D)

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Considering the low rate of patient dropout (almost 12% in the L-carnitine group and 10% in the placebo group), to prevent a biased comparison, all analyses were performed on an ITT analysis dataset [29]

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RNA extraction and sequencing Total RNA was extracted using the traditional TRIzol method

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Stable disease is defined as a disease at least a year from the onset and at least 6 months of stable deformity

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