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Compared with clear cell renal cell carcinomas, Xp11 translocation renal cell carcinomas were younger in age of patients, smaller in tumor size and lower in WHO/ISUP grading

The following mutant strains and alleles were used: N2 (wild type), CB1372 daf-7(e1372) , CB1370 daf-2(e1370) , DA521 egl-4(ad450) , GH10 glo-1(zu437) , DA1402 eat-5(ad1402) , DA465 eat-2(ad465) , RB2742 pept-1(lg1601) , tub-1(nr2004) , tub-1(nr2044)

However, these issues will promptly disappear if the dosage is reduced.

doi: 10.1042/Ebc20170104 254 TsuchidaA.OhnoS.WuW

PMID 32804083

Plemorphic dermal sarcoma typically affects elderly patients and arises in sun-exposed areas (e.g., the scalp)