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We'd genuinely like to know: what area of gastrointestinal research does your work touch on most - barrier biology, innate immunity, tissue integrity, or the gut-systemic connection

A pooled CRISPR screen targeting 200 metabolism-related genes in HeLa cells revealed that glutathione peroxidase 4 ( GPX4 ), a crucial ferroptosis suppressor, was selectively essential in lipoprotein-depleted environments, leading to the hypothesis that lipoproteins may confer protection against ferroptosis

[DOI] [PMC free article] [PubMed] [Google Scholar] 71.Lemberg K.M., Vornov J.J., Rais R., Slusher B.S

Furthermore, phosphorylated Tau plays a role in the antiviral response by potentially acting as a danger signal (Powell-Doherty et al., 2020), and binding sites on Tau proteins have been identified as components for the design of AMPs that when combined with a nuclear localization signal or laminin-receptor derived peptides, display strong activity against E