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To investigate the role of the cGAS-STING pathway in IR-induced lens injury, we established in vitro models by exposing LECs to 16 Gy X-ray irradiation

[DOI] [PubMed] [Google Scholar] 30.Nassini R, Gees M, Harrison S, De Siena G, Materazzi S, Moretto N, Failli P, Preti D, Marchetti N, Cavazzini A, Mancini F, Pedretti P, Nilius B, Patacchini R, Geppetti P

Notably, these metabolic changes are reversible to some extent

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Conclusion In conclusion, a unique pattern of enzymes is produced in the pancreatic beta cell that permits the synthesis by mitochondria of metabolites that are exported to the cytosol to support insulin secretion