glutathione explanation Three essential properties of glutathione:
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& Griffiths, C

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The nuclear glutathione pool is more resistant to depletion by BSO than the cytosolic as it was demonstrated in 3T3 fibroblasts and other human cell lines 87,88 , hence we cannot exclude the possibility that AITC -which presumably acts differently from BSO- is able to deplete efficiently the nuclear pool

Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis

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