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Briefly, during phase 1, cells were grown in Iscoves Modified Dulbecco medium (IMDM) with 15% fetal bovine serum (FBS), 15% human AB serum, 10 ng/mL interleukin-3, 50 ng/mL stem cell factor and 2 IU/mL erythropoietin (Sigma-Aldrich, St

Therefore, we concluded that BPC 157 affects on angiogenesis by activating the NO system through VEGF-A mediated AKT and p38/MAPK signaling pathways (Figure 5A and B)

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Furthermore, diabetes upregulates lysophosphatidylcholine acyltransferase-3 (LPCAT3), facilitating the integration of polyunsaturated fatty acids (PUFA) into phospholipid membranes, and downregulates acyl-CoA thioesterase-1 (ACOT1), which further promotes ferroptosis

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