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Trazodone hydrochloride has been shown to cause increased fetal resorption and other adverse effects on the fetus in the rat when given at dose levels approximately 7.3 to 11 times the maximum recommended human dose (MRHD) of 400 mg/day in adults on a mg/m 2basis

They were unable, however, to reproduce the respective positive finding in a second group of young and healthy subjects

Because the peptide survives gastric passage at approximately 80% structural integrity per the 2016 HPLC data but doesnt survive at 100% oral research protocols typically use higher doses than injectable equivalents to achieve comparable systemic exposure

Because research is limited, side-effect information is not as strong as it is for FDA-approved medications

Not for human consumption, medical use, diagnostic applications, veterinary use, or any other in-vivo application