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Case-control studies have found blood levels of thiamin, TPP, and TMP to be lower in those with dementia of Alzheimer's type (DAT) compared to control subjects (57, 58)

Front Microbiol 8:2296

Circulating nitrite contributes to cardioprotection by remote ischemic preconditioning

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A third series included sulfonate-containing metabolites such as N -carbamyl-taurine, 3-hydroxypropane-1-sulfonic acid, and homotaurine

Rubin J, Hameed B, Gottfried M, Lee W, Sarkar M