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doi: 10.1007/s10863-016-9678-4

In the case of renal impairment, urinary elimination of carnitine increasing, endogenous synthesis decreasing, and poor nutrition as a result of disease-induced anorexia can result in carnitine deficiency

Bauer JM, Verlaan S, Bautmans I, Brandt K, Donini LM, Maggio M, McMurdo ME, Mets T, Seal C, Wijers SL, Ceda GP, De VG, Donders G, Drey M, Greig C, Holmback U, Narici M, McPhee J, Poggiogalle E, Power D, Scafoglieri A, Schultz R, Sieber CC, Cederholm T
J Neuroimmune Pharmacol

(PubMed) Iyer RN, Khan AA, Gupta A, Vajifdar BU, Lokhandwala YY

Kidney or liver disease As the kidneys and liver help create and use L-carnitine, disease in these organs or organ failure Doctors may recommend L-carnitine supplementation in these cases to support the function of the kidneys and liver and prevent deficiency
