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GHK-Cu followed a similar path, removed from Category 2 on the same date, but its PCAC review isn't scheduled until before February 2027

& Zhao, Z.-T

Klein et al., 1988

Scambia G, Testa U, Benedetti Panici P, Foti E, Martucci R, Gadducci A, Perillo A, Facchini V, Peschle C, Mancuso S (1995) Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer

Probiotics repair and fortify these multilayered barriers through multi-target, synergistic mechanisms, and their effects are highly strain-specific ( Prioritizing the chemical and immune barriers, Lactobacillus plantarum HNU082 increases short-chain fatty acid (SCFA) levels, which stimulate goblet cells to secrete MUC2, strengthening the chemical barrier, and reestablishes immune homeostasis by inhibiting NF-B and bidirectionally modulating cytokine production (Wu et al., 2022