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MGMT is a DNA repair enzyme that plays a role in maintaining gene stability directly reversing guanine O6 alkylation through methyl groups, which helps prevent tumorigenesis

10.1038/s41577-019-0127-6 35 DingR.YuX.HuZ.DongY.HuangH.ZhangY.et al (2024)

To provide a more comprehensive exploration of the role of DNA methylation in neurodevelopmental disorders, we have also expanded the discussion on DNA methylation regulation in autism spectrum disorder (ASD) and intellectual disability (ID)
