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Researchers are advancing peptide stability and delivery through altered sequences, carriers, and non-oral routes to increase safety and effectiveness

It has been shown that simple allometric scaling for mAbs that exhibit linear PKs in monkeys can accurately predict human PK within a twofold range.16 However, for mAbs that display nonlinear PK, due to targetmediated drug disposition, allometric scaling results in an overestimation of exposure when below targetsaturating concentrations

Similarly, Honda, Kessoku [65] showed the efficacy of GSH in improving liver function markers in people with non-alcoholic fatty liver disease

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3 , 5154 However, due to the side effects of drugs, in recent years, many patients tend to prefer side-effect-free nasal saline irrigation

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