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Furthermore, tobacco smoke is one factor that significantly contributes to oxidative stress and, consequently, to changes in the epigenetic machinery involving methylation (Mecocci and Polidori, 2012)

Endogenous antioxidant enzymes like catalase, glutathione, and superoxide dismutase actively regulate ROS (Someya and Kim 2021)

Anesthesiology 86, 549557

doi: 10.12659/AJCR.925020 279 TownsendD

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Several herbal formulas have been shown to be efficacious such as Jinhua Qinggan (JHQG) granules, Lianhua Qingwen (LHQW) capsules, Xuanfeibaidu (XFBD) granules, Huashibaidu (HSBD) and Xuebijing (XBJ) 757