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However, they exerted contrasting effects on proteins involved in histone H3-K27 and H3-K4 trimethylation, with DPI causing downregulation and MitoQ causing upregulation

H 2 O 2 detection The release of H 2 O 2 , a reactive oxygen species produced by iRPE cells, was detected via a bioluminescence assay via a ROS-Glo kit (Promega, Charbonnires-les-Bains, France) according to the manufacturers instructions

In this regard, mitochondria (the powerhouse of the cell) generates ATP that energizes a wide range of cellular activities

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