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These PUFAs can inhibit voltage-regulated sodium and calcium currents, thereby exerting an antiarrhythmic action on the heart (99, 100)

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Safety In l-ARG and placebo groups, no significant changes were detected from T0 to T1, regarding clinical and biochemical parameters, except for HDL cholesterol levels, which were significantly increased in l-ARG group ( p = 0.001) and decreased in placebo group ( p = 0.0001)

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