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Conclusions In summary, our findings provide new insights into the molecular mechanisms driving MRTK progression, highlighting YTHDF1 and GSTM2 as potential therapeutic targets for this aggressive pediatric renal tumor

The most-affected pathways include antioxidant defense, DNA repair, ubiquitin-proteasome activity, and TGF-beta signaling

2.3.2.1 Effects of PA on hepatic oxidative stress PA has potential antioxidative activity both in vitro and in vivo

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2017) and the upregulation of growth hormone (receptor) (Chang et al

Six- to eight-week-old female NCI beige-nude-xid (Bethesda, MD, USA) mice were subcutaneously inoculated between shoulder blades with 2530 10 6 MM cells using matrigel (BD Biosciences)