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Cachexia is caused by an inflammatory reaction that involves the molecules TNF- and IL-6, which play a role in radiation resistance

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The defects in LMP-1 localization could result from GLO-3 and CCZ-1 functioning in the AP-3 pathway independently of regulating GLO-1

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Pleiotropic effects of the carnitine pool Carnitine can be combined with fatty acid chains of different lengths to derive a variety of acylcarnitines, which are amphiphilic because they contain hydrophilic quaternary ammonium groups and hydrophobic carbon chains [5], and acylcarnitines of different chain lengths have diverse chemical structure and metabolic pathways, making them widely involved in pathophysiology

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