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Preclinical studies focus on metabolism, cartilage signaling, and obesity models

Sonic hedgehog signaling inhibition provides opportunities for targeted therapy by sulforaphane in regulating pancreatic cancer stem cell self-renewal

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In cuproptosis, copper in cells can bind to lipoylated components of the TCA cycle, resulting in the aggregation of copper-bound lipoylated mitochondrial proteins

doi: 10.1248/bpb.26.840 365 LinWLWangCJTsaiYYLiuCLHwangJMTsengTH