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Moreover, given that SNARE function is modulated by calcium signaling and that Pb can act as a calcium mimic, Pb 2+ may competitively interfere with calcium-dependent vesicle fusion, further disrupting SNARE-mediated exocytosis

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Interestingly, this was also reflected in the protein abundance level of antioxidative enzymes

Hence, understanding the mechanism concerning the effect of HDL on mitochondria will be beneficial for clarifying the pathogenesis of diseases including metabolic defects and providing new ideas for treatment

Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinsons disease induced by MPTP neurodegeneration in mice

Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells