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If you're already using a high concentration of niacinamide elsewhere, you might want to space them out to avoid over-delivery of a single ingredient

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Keratosis pilaris is a condition in which keratin collects in and plugs hair follicles, resulting in the formation of patches of rough bumps.

According to the manufacturer, the usual daily recommended amounts of cyanocobalamin, vitamin B12 for lactating women should be taken maternally during breast-feeding (see Dosage)