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It was shown that TLR3 stimulation by the injection of viral mimic Poly(I: C) leads to a decrease in locomotor activity and exploratory rearing behavior in the open field (OF) test, as well as a decrease in water and food intake and 9 days of alternate day fasting exacerbate these effects (66)

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Reference: Mylan Product Monograph

[DOI] [PubMed] [Google Scholar] Toomes C, Bottomley HM, Jackson RM, Towns KV, Scott S, Mackey DA, Craig JE, Jiang L, Yang Z, Trembath R, et al

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