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Ideal affinity support should allow unhindered access of a solute to the immobilized ligand

Data availability All data generated or analysed during this study are included in this research article

[Consulta: 12 novembre 2021].

The ADWT-induced increases in glycolysis are mediated by early adenovirus gene product E4ORF1 binding to cellular MYC to direct transcription of specific glycolytic enzymes, including HK2 and PFKM, and an adenovirus containing the D68A point mutation in E4ORF1 that prevents binding to MYC does not replicate as well as ADWT [2]

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