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Bott et al , 2015

4 The authors own conclusion is the one worth quoting in spirit: the lipolytic actions of hGH and AOD-9604 are not mediated directly through the 3-AR, even though both compounds increase 3-AR expression, which may in turn contribute to enhanced lipolytic sensitivity over time

Smoking not only contributes to gum inflammation, but is also likely to further worsen periodontitis through stimulating the immune system and affecting the microbial community

doi: 10.1158/2159-8290.CD-20-0738 95 JeongSSavinoAMChirayilRBarinEChengYParkSMet al

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Although multiple pathways are involved in mediating tissue damage, including the polyol pathway, advanced glycation end product formation, protein kinase C activation, and the hexosamine pathway, a common feature is increased oxidative stress marked by elevated levels of reactive oxygen species (ROS) (1)