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Description
"Beneficial effects of l-carnitine supplementation for weight management in overweight and obese adults: An updated systematic review and dose-response meta-analysis of randomized controlled trials." Pharmacological Research, January 2020, Brass, E P
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CATcatalase
Carnitine can protect human retinal pigment epithelial (RPE) cells from oxidative damage induced by H 2 O 2 [319]
However, excessive BCACs produced by the breakdown of branched-chain amino acids can interfere with normal mitochondrial function and cause energy metabolism disorders [11]
In hepatocellular carcinoma (HCC), LCACs are effectively loaded into the mitochondria of lymphocytes, resulting in the inhibition of invariant natural killer T (iNKT) cell expansion and the promotion of their senescence while simultaneously facilitating tumor evasion of immune surveillance [66]
