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Well known as the treatment for acetaminophen-induced hepatotoxicity [9], NAC also has antioxidant, anti-inflammatory and antinociceptive effects through different molecular pathways [10]
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doi: 10.3390/nano12071099, [DOI] [PMC free article] [PubMed] [Google Scholar] 202.des Rieux A, Fievez V, Garinot M, Schneider Y-J, Prat V
Whereas certain metabolites of bile acids are found to promote ferroptosis [165]
In patients with locally advanced, metastatic, and/or refractory solid tumors and hematological malignancies, CB839 is being evaluated in open-label phase I clinical trials (NCT02071862, NCT02071888, NCT02771626)
