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10.1007/s10517-016-3370-x [DOI] [PubMed] [Google Scholar] 34.Khavinson VK, Kopylov AT, Vaskovsky BV, Ryzhak GA, Linkova NS

[DOI] [PubMed] [Google Scholar] 15.Pitcher J, Lohse MJ, Codina J, Caron MG, Lefkowitz RJ

The results demonstrated that BV2-metformin-loaded PLGA treatment reduced TNF- and GFAP expression, confirming suppression of neuroinflammation, while p62 levels were increased, indicating enhanced autophagy

These disease models can incorporate the physiological and functional properties of healthy BBBs as well as the heterogeneity of different CNS diseases to enable personalized medicine

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