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M., Wei X., et al

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Increasing blood and oxygen flow

But in chronically degenerated tissue, there's no active inflammation left

Specific IgG detection via ELISA Collagen type II (CII)-specific antibodies were detected by ELISA using high-binding plates (Nunc) coated overnight with 10 g/ml mouse or chicken CII

BBB dysfunction in these pathologies may result in compromised transport and permeability properties of the barrier as well as in alterations in cerebrovascular regulatory mechanisms of blood flow, with ensuing perturbed signalling between brain endothelium and associated cells, such as glia and neurons