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Myostatin regulates preadipocyte differentiation and lipid metabolism of adipocyte via ERK1/2

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Interestingly, one of the proposed IGF-1 mechanisms in the context of CVDs is the prevention of atherosclerotic plaque instability through VSMCs phenotype modulation and anti-apoptotic effects (59, 60)

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In addition to heightened fibroblast activity, which plays a key role in collagen synthesis, tissue repair, and regeneration, there appeared to be a possible rise in mast cell activation
