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The reasons why hexane and water do not mix are complex, but the following gives you a glimpse at why hexane is insoluble in water

Boertlein A., Brgerhospital Stuttgart, Department of Neurology

doi: 10.1186/s13229-017-0165-5

10.1111/j.1471-4159.1987.tb05737.x 153 MogiM.HaradaM.RiedererP.NarabayashiH.FujitaK.NagatsuT

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Additionally, intravenous infusion of magnesium sulphate remains the drug of choice to prevent and control convulsions caused by eclampsia, significantly reducing maternal mortality related to eclampsia[392]